| Image | Item No. | Description |
| 40454-1 (Inv) | Spider-Man vs. Venom and Iron Venom blister pack
50 Parts, 4 Minifigures, 2021
Catalog: Sets: Super Heroes: Spider-Man |
| 76154-1 (Inv) | Deviant Ambush!
185 Parts, 3 Minifigures, 2021
Catalog: Sets: Super Heroes: Eternals |
| 76156-1 (Inv) | Rise of the Domo
1016 Parts, 6 Minifigures, 2021
Catalog: Sets: Super Heroes: Eternals |
| 76172-1 (Inv) | Spider-Man and Sandman Showdown
38 Parts, 2 Minifigures, 2021
Catalog: Sets: Super Heroes: Spider-Man |
| 76173-1 (Inv) | Spider-Man and Ghost Rider vs. Carnage
194 Parts, 3 Minifigures, 2021
Catalog: Sets: Super Heroes: Spider-Man |
| 76176-1 (Inv) | Escape from The Ten Rings
305 Parts, 4 Minifigures, 2021
Catalog: Sets: Super Heroes: Shang-Chi |
| 76177-1 (Inv) | Battle at the Ancient Village
385 Parts, 4 Minifigures, 2021
Catalog: Sets: Super Heroes: Shang-Chi |
| 76178-1 (Inv) | Daily Bugle
3592 Parts, 25 Minifigures, 2021
Catalog: Sets: Super Heroes: Spider-Man |
| 76179-1 (Inv) | Batman & Selina Kyle Motorcycle Pursuit
140 Parts, 2 Minifigures, 2021
Catalog: Sets: Super Heroes: The Batman |
| 76180-1 (Inv) | Batman vs. The Joker: Batmobile Chase
122 Parts, 3 Minifigures, 2021
Catalog: Sets: Super Heroes: Batman II |
| 76181-1 (Inv) | Batmobile: The Penguin Chase
383 Parts, 2 Minifigures, 2021
Catalog: Sets: Super Heroes: The Batman |
| 76183-1 (Inv) | Batcave: The Riddler Face-off
556 Parts, 6 Minifigures, 2021
Catalog: Sets: Super Heroes: The Batman |
| 76185-1 (Inv) | Spider-Man at the Sanctum Workshop
339 Parts, 4 Minifigures, 2021
Catalog: Sets: Super Heroes: Spider-Man No Way Home |
| 76187-1 (Inv) | Venom
565 Parts, 2021
Catalog: Sets: Super Heroes: Sculptures: Spider-Man |
| 76191-1 (Inv) | Infinity Gauntlet
590 Parts, 2021
Catalog: Sets: Super Heroes: Sculptures: The Infinity Saga |
| 76192-1 (Inv) | Avengers: Endgame Final Battle
494 Parts, 8 Minifigures, 2021
Catalog: Sets: Super Heroes: The Infinity Saga |
| 76193-1 (Inv) | The Guardians' Ship
1878 Parts, 6 Minifigures, 2021
Catalog: Sets: Super Heroes: The Infinity Saga |
| 76194-1 (Inv) | Tony Stark’s Sakaarian Iron Man
355 Parts, 3 Minifigures, 2021
Catalog: Sets: Super Heroes: What If...? |
| 76195-1 (Inv) | Spider-Man's Drone Duel
188 Parts, 2 Minifigures, 2021
Catalog: Sets: Super Heroes: Spider-Man No Way Home |
| 76200-1 (Inv) | Bro Thor’s New Asgard
253 Parts, 3 Minifigures, 2021
Catalog: Sets: Super Heroes: The Infinity Saga |
| 76201-1 (Inv) | Captain Carter & The Hydra Stomper
332 Parts, 3 Minifigures, 2021
Catalog: Sets: Super Heroes: What If...? |
| 76237-1 (Inv) | Sanctuary II: Endgame Battle
310 Parts, 3 Minifigures, 2021
Catalog: Sets: Super Heroes: The Infinity Saga |
| 76239-1 (Inv) | Batmobile Tumbler: Scarecrow Showdown
414 Parts, 2 Minifigures, 2021
Catalog: Sets: Super Heroes: The Dark Knight Trilogy |
| 76240-1 (Inv) | Batman Batmobile Tumbler
2040 Parts, 2 Minifigures, 2021
Catalog: Sets: Super Heroes: The Dark Knight Trilogy |
| 242105-1 (Inv) | Thor foil pack
4 Parts, 1 Minifigure, 2021
Catalog: Sets: Super Heroes: Avengers |